Thyroid hormone receptor-β agonists prevent hepatic steatosis in fat-fed rats but impair insulin sensitivity via discrete pathways.

Vatner, Daniel F

Thyroid hormone receptor-β agonists prevent hepatic steatosis in fat-fed rats but impair insulin sensitivity via discrete pathways. [electronic resource] - American journal of physiology. Endocrinology and metabolism Jul 2013 - E89-100 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

1522-1555

10.1152/ajpendo.00573.2012 doi


Acetates--pharmacology
Anilides--pharmacology
Animals
Dietary Fats--pharmacology
Fatty Liver--drug therapy
Gene Expression--drug effects
Gluconeogenesis--drug effects
Glucose Transporter Type 4--metabolism
Hyperglycemia--chemically induced
Hyperinsulinism--chemically induced
Insulin Resistance--physiology
Male
Muscle, Skeletal--drug effects
Non-alcoholic Fatty Liver Disease
Phenols--pharmacology
Rats
Rats, Sprague-Dawley
Signal Transduction--drug effects
Thyroid Hormone Receptors beta--agonists
Triglycerides--metabolism