Structure-activity relationships for 4-anilinoquinoline derivatives as inhibitors of the DNA methyltransferase enzyme DNMT1.

Gamage, Swarna A

Structure-activity relationships for 4-anilinoquinoline derivatives as inhibitors of the DNA methyltransferase enzyme DNMT1. [electronic resource] - Bioorganic & medicinal chemistry Jun 2013 - 3147-53 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1464-3391

10.1016/j.bmc.2013.03.033 doi


Aniline Compounds--chemical synthesis
Antineoplastic Agents--chemical synthesis
DNA (Cytosine-5-)-Methyltransferase 1
DNA (Cytosine-5-)-Methyltransferases--antagonists & inhibitors
Gene Expression--drug effects
HCT116 Cells
Humans
Neoplasm Proteins--antagonists & inhibitors
Quinolines--chemical synthesis
Structure-Activity Relationship