Dichloroacetate at therapeutic concentration alters glucose metabolism and induces regulatory T-cell differentiation in alloreactive human lymphocytes.

Eleftheriadis, Theodoros

Dichloroacetate at therapeutic concentration alters glucose metabolism and induces regulatory T-cell differentiation in alloreactive human lymphocytes. [electronic resource] - Journal of basic and clinical physiology and pharmacology 2013 - 271-6 p. digital

Publication Type: Journal Article

2191-0286

10.1515/jbcpp-2013-0001 doi


Aerobiosis
Autoimmunity--drug effects
Cell Culture Techniques
Cell Differentiation--drug effects
Cell Proliferation--drug effects
Cell Survival--drug effects
Cells, Cultured
Dichloroacetic Acid--pharmacokinetics
Dose-Response Relationship, Drug
Forkhead Transcription Factors--genetics
Glucose--metabolism
Glycolysis--drug effects
Humans
Interleukin-10--biosynthesis
Leukocytes, Mononuclear--cytology
T-Lymphocytes, Regulatory--cytology