Synthesis and evaluation of biphenyl compounds as kinesin spindle protein inhibitors.
Holland, Jason P
Synthesis and evaluation of biphenyl compounds as kinesin spindle protein inhibitors. [electronic resource] - Chemistry & biodiversity Apr 2013 - 538-55 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1612-1880
10.1002/cbdv.201200400 doi
Adenosine Triphosphate--metabolism
Antimitotic Agents--chemical synthesis
Biphenyl Compounds--chemical synthesis
Cell Cycle Proteins--metabolism
Cell Line, Tumor
Cell Proliferation--drug effects
Enzyme Inhibitors--chemical synthesis
HCT116 Cells
Humans
Kinesins--antagonists & inhibitors
M Phase Cell Cycle Checkpoints--drug effects
MCF-7 Cells
Structure-Activity Relationship
Thiourea--chemistry
Synthesis and evaluation of biphenyl compounds as kinesin spindle protein inhibitors. [electronic resource] - Chemistry & biodiversity Apr 2013 - 538-55 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1612-1880
10.1002/cbdv.201200400 doi
Adenosine Triphosphate--metabolism
Antimitotic Agents--chemical synthesis
Biphenyl Compounds--chemical synthesis
Cell Cycle Proteins--metabolism
Cell Line, Tumor
Cell Proliferation--drug effects
Enzyme Inhibitors--chemical synthesis
HCT116 Cells
Humans
Kinesins--antagonists & inhibitors
M Phase Cell Cycle Checkpoints--drug effects
MCF-7 Cells
Structure-Activity Relationship
Thiourea--chemistry