Germline BRCA mutations are associated with higher risk of nodal involvement, distant metastasis, and poor survival outcomes in prostate cancer.

Castro, Elena

Germline BRCA mutations are associated with higher risk of nodal involvement, distant metastasis, and poor survival outcomes in prostate cancer. [electronic resource] - Journal of clinical oncology : official journal of the American Society of Clinical Oncology May 2013 - 1748-57 p. digital

Publication Type: Journal Article

1527-7755

10.1200/JCO.2012.43.1882 doi


Adult
Aged
Aged, 80 and over
Antineoplastic Agents, Hormonal--therapeutic use
Antineoplastic Combined Chemotherapy Protocols--therapeutic use
BRCA1 Protein--genetics
BRCA2 Protein--genetics
Brachytherapy
Follow-Up Studies
Genetic Predisposition to Disease
Germ-Line Mutation
Heterozygote
Humans
Kaplan-Meier Estimate
Lymph Nodes--pathology
Lymphatic Metastasis
Male
Middle Aged
Neoplasm Grading
Neoplasm Staging
Nomograms
Palliative Care--methods
Phenotype
Predictive Value of Tests
Prognosis
Proportional Hazards Models
Prostatectomy
Prostatic Neoplasms--genetics
Radiotherapy, Adjuvant
Retrospective Studies
Risk Assessment
Risk Factors