Upregulation of cytoprotective defense mechanisms and hypoxia-responsive proteins imparts tolerance to acute hypobaric hypoxia.

Jain, Kanika

Upregulation of cytoprotective defense mechanisms and hypoxia-responsive proteins imparts tolerance to acute hypobaric hypoxia. [electronic resource] - High altitude medicine & biology Mar 2013 - 65-77 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1557-8682

10.1089/ham.2012.1064 doi


Altitude
Animals
Atmospheric Pressure
Catalase--metabolism
Creatine Kinase, MB Form--metabolism
Dyspnea--etiology
Endothelin-1--metabolism
Erythropoietin--metabolism
HSP70 Heat-Shock Proteins--metabolism
HSP90 Heat-Shock Proteins--metabolism
Heme Oxygenase-1--metabolism
Hypoxia--pathology
Hypoxia-Inducible Factor 1, alpha Subunit--metabolism
Male
Malondialdehyde--metabolism
Myocarditis--etiology
Myocardium--metabolism
Nitric Oxide--metabolism
Oxidative Stress
Protein Carbonylation
Rats
Rats, Sprague-Dawley
Reactive Oxygen Species--metabolism
Superoxide Dismutase--metabolism
Time Factors
Up-Regulation
Vascular Endothelial Growth Factor A--metabolism