Inhibition of histone deacetylase impacts cancer stem cells and induces epithelial-mesenchyme transition of head and neck cancer.

Giudice, Fernanda S

Inhibition of histone deacetylase impacts cancer stem cells and induces epithelial-mesenchyme transition of head and neck cancer. [electronic resource] - PloS one 2013 - e58672 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1932-6203

10.1371/journal.pone.0058672 doi


Acetylation
Carcinoma, Squamous Cell--drug therapy
Cell Line, Tumor
Chromatin--genetics
Epigenesis, Genetic--drug effects
Epithelial-Mesenchymal Transition--drug effects
Head and Neck Neoplasms--drug therapy
Histone Deacetylase Inhibitors--pharmacology
Humans
Neoplasm Invasiveness
Neoplastic Stem Cells--drug effects
Polycomb Repressive Complex 1--genetics
Squamous Cell Carcinoma of Head and Neck
Tumor Microenvironment--drug effects