AAV-mediated expression of an ADAMTS13 variant prevents shigatoxin-induced thrombotic thrombocytopenic purpura.

Jin, Sheng-Yu

AAV-mediated expression of an ADAMTS13 variant prevents shigatoxin-induced thrombotic thrombocytopenic purpura. [electronic resource] - Blood May 2013 - 3825-9, S1-3 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1528-0020

10.1182/blood-2013-02-486779 doi


ADAMTS13 Protein
Animals
Codon, Nonsense--physiology
Cytoprotection--genetics
Dependovirus
Genetic Therapy--methods
Genetic Vectors--genetics
Metalloendopeptidases--genetics
Mice
Mice, Knockout
Purpura, Thrombotic Thrombocytopenic--chemically induced
Shiga Toxin 2--toxicity
Transformation, Genetic