A prospective, randomized Phase II clinical trial to evaluate the effect of combined hyperbaric and normobaric hyperoxia on cerebral metabolism, intracranial pressure, oxygen toxicity, and clinical outcome in severe traumatic brain injury.

Rockswold, Sarah B

A prospective, randomized Phase II clinical trial to evaluate the effect of combined hyperbaric and normobaric hyperoxia on cerebral metabolism, intracranial pressure, oxygen toxicity, and clinical outcome in severe traumatic brain injury. [electronic resource] - Journal of neurosurgery Jun 2013 - 1317-28 p. digital

Publication Type: Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural

1933-0693

10.3171/2013.2.JNS121468 doi


Adult
Biomarkers--metabolism
Brain--metabolism
Brain Injuries--metabolism
Combined Modality Therapy
Female
Glasgow Outcome Scale
Humans
Hyperbaric Oxygenation--methods
Intracranial Hypertension--epidemiology
Intracranial Pressure--physiology
Linear Models
Male
Oxygen--metabolism
Prospective Studies
Risk Factors
Severity of Illness Index
Treatment Outcome