Acute ketamine induces hippocampal synaptic depression and spatial memory impairment through dopamine D1/D5 receptors.

Duan, Ting-Ting

Acute ketamine induces hippocampal synaptic depression and spatial memory impairment through dopamine D1/D5 receptors. [electronic resource] - Psychopharmacology Aug 2013 - 451-61 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1432-2072

10.1007/s00213-013-3048-2 doi


Anesthetics, Dissociative--administration & dosage
Animals
Benzazepines--pharmacology
CA1 Region, Hippocampal--drug effects
Dose-Response Relationship, Drug
Ketamine--administration & dosage
Male
Maze Learning--drug effects
Memory Disorders--chemically induced
Rats
Rats, Sprague-Dawley
Receptors, Dopamine D1--antagonists & inhibitors
Receptors, Dopamine D5--antagonists & inhibitors
Spatial Behavior--drug effects
Synaptic Transmission--drug effects