Biased and constitutive signaling in the CC-chemokine receptor CCR5 by manipulating the interface between transmembrane helices 6 and 7.

Steen, Anne

Biased and constitutive signaling in the CC-chemokine receptor CCR5 by manipulating the interface between transmembrane helices 6 and 7. [electronic resource] - The Journal of biological chemistry May 2013 - 12511-21 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1083-351X

10.1074/jbc.M112.449587 doi


Amino Acid Motifs
Amino Acid Substitution
Animals
COS Cells
Chlorocebus aethiops
Humans
Mutation, Missense
Protein Structure, Tertiary
Receptors, CCR5--genetics
Signal Transduction