Inhibition of TGF-β1-receptor posttranslational core fucosylation attenuates rat renal interstitial fibrosis.

Shen, Nan

Inhibition of TGF-β1-receptor posttranslational core fucosylation attenuates rat renal interstitial fibrosis. [electronic resource] - Kidney international Jul 2013 - 64-77 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1523-1755

10.1038/ki.2013.82 doi


Activin Receptors, Type I--metabolism
Animals
Bone Morphogenetic Protein Receptors, Type I--metabolism
Cells, Cultured
Disease Models, Animal
Disease Progression
Fibrosis
Fucose--metabolism
Fucosyltransferases--genetics
Gene Expression Regulation, Enzymologic
Gene Transfer Techniques
Humans
Kidney--metabolism
Kidney Diseases--genetics
Male
Protein Processing, Post-Translational
Protein Serine-Threonine Kinases--metabolism
RNA Interference
RNA, Messenger--metabolism
Rats
Rats, Wistar
Receptor, Transforming Growth Factor-beta Type I
Receptor, Transforming Growth Factor-beta Type II
Receptors, Transforming Growth Factor beta--genetics
Time Factors
Transforming Growth Factor beta1--metabolism
Ureteral Obstruction--complications