Evidence for a common mechanism of SIRT1 regulation by allosteric activators.

Hubbard, Basil P

Evidence for a common mechanism of SIRT1 regulation by allosteric activators. [electronic resource] - Science (New York, N.Y.) Mar 2013 - 1216-9 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

1095-9203

10.1126/science.1231097 doi


Allosteric Regulation
Amino Acid Motifs
Amino Acid Sequence
Amino Acid Substitution
Animals
Cells, Cultured
Enzyme Activation
Forkhead Box Protein O3
Forkhead Transcription Factors--chemistry
Glutamic Acid--chemistry
Heterocyclic Compounds, 4 or More Rings--chemistry
Humans
Hydrophobic and Hydrophilic Interactions
Mice
Molecular Sequence Data
Myoblasts--drug effects
Protein Structure, Tertiary
Resveratrol
Sirtuin 1--chemistry
Stilbenes--chemistry
Substrate Specificity