Cancerous inhibitor of protein phosphatase 2A mediates bortezomib-induced autophagy in hepatocellular carcinoma independent of proteasome.

Yu, Hui-Chuan

Cancerous inhibitor of protein phosphatase 2A mediates bortezomib-induced autophagy in hepatocellular carcinoma independent of proteasome. [electronic resource] - PloS one 2013 - e55705 p. digital

Publication Type: Journal Article

1932-6203

10.1371/journal.pone.0055705 doi


Acridine Orange
Autoantigens--metabolism
Autophagy--drug effects
Blotting, Western
Boronic Acids--metabolism
Bortezomib
Carcinoma, Hepatocellular--metabolism
Cell Line, Tumor
Dose-Response Relationship, Drug
Flow Cytometry
Fluorescent Antibody Technique
Gene Expression Regulation--drug effects
Humans
Intracellular Signaling Peptides and Proteins
Liver Neoplasms--metabolism
Membrane Proteins--metabolism
Microscopy, Fluorescence
Phosphorylation
Proteasome Endopeptidase Complex--metabolism
Protein Phosphatase 2--antagonists & inhibitors
Pyrazines--metabolism
Time Factors