Application of knockout mouse models to investigate the influence of FcγR on the pharmacokinetics and anti-platelet effects of MWReg30, a monoclonal anti-GPIIb antibody.
Abuqayyas, Lubna
Application of knockout mouse models to investigate the influence of FcγR on the pharmacokinetics and anti-platelet effects of MWReg30, a monoclonal anti-GPIIb antibody. [electronic resource] - International journal of pharmaceutics Feb 2013 - 185-92 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1873-3476
10.1016/j.ijpharm.2013.01.001 doi
Animals
Antibodies, Monoclonal--blood
Immunoglobulin G--immunology
Mice
Mice, Inbred C57BL
Mice, Knockout
Platelet Aggregation Inhibitors--blood
Platelet Count
Platelet Membrane Glycoprotein IIb--immunology
Receptors, IgG--physiology
Thrombocytopenia--blood
Tissue Distribution
Application of knockout mouse models to investigate the influence of FcγR on the pharmacokinetics and anti-platelet effects of MWReg30, a monoclonal anti-GPIIb antibody. [electronic resource] - International journal of pharmaceutics Feb 2013 - 185-92 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1873-3476
10.1016/j.ijpharm.2013.01.001 doi
Animals
Antibodies, Monoclonal--blood
Immunoglobulin G--immunology
Mice
Mice, Inbred C57BL
Mice, Knockout
Platelet Aggregation Inhibitors--blood
Platelet Count
Platelet Membrane Glycoprotein IIb--immunology
Receptors, IgG--physiology
Thrombocytopenia--blood
Tissue Distribution