Sorting nexin 2-mediated membrane trafficking of c-Met contributes to sensitivity of molecular-targeted drugs.

Ogi, Sayaka

Sorting nexin 2-mediated membrane trafficking of c-Met contributes to sensitivity of molecular-targeted drugs. [electronic resource] - Cancer science May 2013 - 573-83 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1349-7006

10.1111/cas.12117 doi


Antineoplastic Agents--pharmacology
Cell Line, Tumor
Cell Proliferation--drug effects
Down-Regulation--drug effects
Drug Resistance, Neoplasm
ErbB Receptors--genetics
Gefitinib
Humans
Lung Neoplasms--drug therapy
Lysosomes--drug effects
Membrane Transport Proteins--genetics
Molecular Targeted Therapy
Mutation--drug effects
Protein Transport
Proto-Oncogene Proteins c-met--genetics
Quinazolines--pharmacology
Sorting Nexins--genetics