BMP and TGF-β pathway mediators are critical upstream regulators of Wnt signaling during midbrain dopamine differentiation in human pluripotent stem cells.

Cai, Jingli

BMP and TGF-β pathway mediators are critical upstream regulators of Wnt signaling during midbrain dopamine differentiation in human pluripotent stem cells. [electronic resource] - Developmental biology Apr 2013 - 62-73 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1095-564X

10.1016/j.ydbio.2013.01.012 doi


Blotting, Western
Bone Morphogenetic Proteins--antagonists & inhibitors
Cell Differentiation--physiology
Cell Line
Dopaminergic Neurons--cytology
Gene Expression Regulation, Developmental--drug effects
Humans
Immunohistochemistry
Intercellular Signaling Peptides and Proteins
Membrane Proteins
Mesencephalon--cytology
Nerve Tissue Proteins--metabolism
Pluripotent Stem Cells--metabolism
Pyrazoles--pharmacology
Pyrimidines--pharmacology
RNA, Small Interfering--genetics
RNA-Binding Proteins--metabolism
Real-Time Polymerase Chain Reaction
Transforming Growth Factor beta--antagonists & inhibitors
Wnt Signaling Pathway--drug effects