A novel B-domain O-glycoPEGylated FVIII (N8-GP) demonstrates full efficacy and prolonged effect in hemophilic mice models.
Stennicke, Henning R
A novel B-domain O-glycoPEGylated FVIII (N8-GP) demonstrates full efficacy and prolonged effect in hemophilic mice models. [electronic resource] - Blood Mar 2013 - 2108-16 p. digital
Publication Type: Evaluation Study; Journal Article
1528-0020
10.1182/blood-2012-01-407494 doi
Animals
CHO Cells
Cells, Cultured
Cricetinae
Cricetulus
Disease Models, Animal
Factor VIII--administration & dosage
Female
Glycosylation
Hemophilia A--drug therapy
Humans
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Models, Biological
Polyethylene Glycols--administration & dosage
Rabbits
Rats
Rats, Sprague-Dawley
Time Factors
Treatment Outcome
A novel B-domain O-glycoPEGylated FVIII (N8-GP) demonstrates full efficacy and prolonged effect in hemophilic mice models. [electronic resource] - Blood Mar 2013 - 2108-16 p. digital
Publication Type: Evaluation Study; Journal Article
1528-0020
10.1182/blood-2012-01-407494 doi
Animals
CHO Cells
Cells, Cultured
Cricetinae
Cricetulus
Disease Models, Animal
Factor VIII--administration & dosage
Female
Glycosylation
Hemophilia A--drug therapy
Humans
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Models, Biological
Polyethylene Glycols--administration & dosage
Rabbits
Rats
Rats, Sprague-Dawley
Time Factors
Treatment Outcome