Synthesis and biological evaluation of substituted benzoxazoles as inhibitors of mPGES-1: use of a conformation-based hypothesis to facilitate compound design.
Walker, Daniel P
Synthesis and biological evaluation of substituted benzoxazoles as inhibitors of mPGES-1: use of a conformation-based hypothesis to facilitate compound design. [electronic resource] - Bioorganic & medicinal chemistry letters Feb 2013 - 1120-6 p. digital
Publication Type: Journal Article
1464-3405
10.1016/j.bmcl.2012.11.107 doi
Benzoxazoles--chemical synthesis
Drug Design
Enzyme Inhibitors--chemical synthesis
Humans
Intramolecular Oxidoreductases--antagonists & inhibitors
Models, Molecular
Molecular Conformation
Prostaglandin-E Synthases
Structure-Activity Relationship
Synthesis and biological evaluation of substituted benzoxazoles as inhibitors of mPGES-1: use of a conformation-based hypothesis to facilitate compound design. [electronic resource] - Bioorganic & medicinal chemistry letters Feb 2013 - 1120-6 p. digital
Publication Type: Journal Article
1464-3405
10.1016/j.bmcl.2012.11.107 doi
Benzoxazoles--chemical synthesis
Drug Design
Enzyme Inhibitors--chemical synthesis
Humans
Intramolecular Oxidoreductases--antagonists & inhibitors
Models, Molecular
Molecular Conformation
Prostaglandin-E Synthases
Structure-Activity Relationship