Salsolinol induced apoptotic changes in neural stem cells: amelioration by neurotrophin support.

Shukla, A

Salsolinol induced apoptotic changes in neural stem cells: amelioration by neurotrophin support. [electronic resource] - Neurotoxicology Mar 2013 - 50-61 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1872-9711

10.1016/j.neuro.2012.12.005 doi


Animals
Apoptosis--drug effects
Brain-Derived Neurotrophic Factor--metabolism
Caspase 3--metabolism
Cell Survival--drug effects
Cells, Cultured
Culture Media, Conditioned--metabolism
Cyclic AMP Response Element-Binding Protein--metabolism
Cytoprotection
Dose-Response Relationship, Drug
Glial Cell Line-Derived Neurotrophic Factor--metabolism
Glycogen Synthase Kinase 3--metabolism
Glycogen Synthase Kinase 3 beta
In Situ Nick-End Labeling
Isoquinolines--toxicity
Mitochondria--drug effects
Neural Stem Cells--drug effects
Olfactory Bulb--metabolism
Paracrine Communication
Phosphatidylinositol 3-Kinase--metabolism
Phosphoinositide-3 Kinase Inhibitors
Phosphorylation
Protein Kinase Inhibitors--pharmacology
Proto-Oncogene Proteins c-akt--metabolism
Proto-Oncogene Proteins c-bcl-2--metabolism
Rats
Rats, Wistar
Signal Transduction--drug effects
Time Factors
bcl-2-Associated X Protein--metabolism