Identification of benzofuran central cores for the inhibition of leukotriene A(4) hydrolase.

Eccles, Wendy

Identification of benzofuran central cores for the inhibition of leukotriene A(4) hydrolase. [electronic resource] - Bioorganic & medicinal chemistry letters Feb 2013 - 811-5 p. digital

Publication Type: Journal Article

1464-3405

10.1016/j.bmcl.2012.11.074 doi


Animals
Benzofurans--chemistry
Dose-Response Relationship, Drug
Enzyme Activation--drug effects
Enzyme Inhibitors--chemistry
Epoxide Hydrolases--antagonists & inhibitors
Humans
Inhibitory Concentration 50
Mice
Molecular Structure
Rats
Rats, Sprague-Dawley