Nek1 phosphorylates Von Hippel-Lindau tumor suppressor to promote its proteasomal degradation and ciliary destabilization.

Patil, Mallikarjun

Nek1 phosphorylates Von Hippel-Lindau tumor suppressor to promote its proteasomal degradation and ciliary destabilization. [electronic resource] - Cell cycle (Georgetown, Tex.) Jan 2013 - 166-71 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

1551-4005

10.4161/cc.23053 doi


Amino Acid Sequence
Cell Cycle Proteins--genetics
Cilia--drug effects
HEK293 Cells
Humans
Molecular Sequence Data
Mutation
NIMA-Related Kinase 1
Nocodazole--pharmacology
Phosphorylation
Proteasome Endopeptidase Complex--metabolism
Protein Serine-Threonine Kinases--genetics
Transfection
Tubulin Modulators--pharmacology
Von Hippel-Lindau Tumor Suppressor Protein--genetics