Class I and class II histone deacetylases are potential therapeutic targets for treating pancreatic cancer.

Wang, Guan

Class I and class II histone deacetylases are potential therapeutic targets for treating pancreatic cancer. [electronic resource] - PloS one 2012 - e52095 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0052095 doi


Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Cell Cycle Checkpoints--drug effects
Cell Death--drug effects
Cell Division--drug effects
Cell Line, Tumor
Cyclin-Dependent Kinase Inhibitor p21--metabolism
DNA Breaks, Double-Stranded
Epithelial Cells--drug effects
G2 Phase--drug effects
Histone Deacetylase Inhibitors--pharmacology
Histone Deacetylases--metabolism
Histones--metabolism
Humans
Molecular Targeted Therapy
Pancreatic Neoplasms--drug therapy
Tubulin--metabolism