Telmisartan plus propranolol improves liver fibrosis and bile duct proliferation in the PSC-like Abcb4-/- mouse model.

Mende, Susanne

Telmisartan plus propranolol improves liver fibrosis and bile duct proliferation in the PSC-like Abcb4-/- mouse model. [electronic resource] - Digestive diseases and sciences May 2013 - 1271-81 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1573-2568

10.1007/s10620-012-2499-3 doi


ATP Binding Cassette Transporter, Subfamily B--genetics
Adrenergic beta-Antagonists--pharmacology
Animals
Benzimidazoles--pharmacology
Benzoates--pharmacology
Bile Ducts--drug effects
Cholangitis, Sclerosing--drug therapy
Collagen Type I--metabolism
Collagen Type I, alpha 1 Chain
Cytokines--metabolism
Disease Models, Animal
Drug Evaluation, Preclinical
Drug Therapy, Combination
Liver--drug effects
Mice
Mice, Inbred BALB C
Mice, Knockout
Myofibroblasts--metabolism
Propranolol--pharmacology
RNA, Messenger--metabolism
Receptor, Angiotensin, Type 1--therapeutic use
Telmisartan
ATP-Binding Cassette Sub-Family B Member 4