Antinociceptive effects of the N-acylethanolamine acid amidase inhibitor ARN077 in rodent pain models.

Sasso, Oscar

Antinociceptive effects of the N-acylethanolamine acid amidase inhibitor ARN077 in rodent pain models. [electronic resource] - Pain Mar 2013 - 350-360 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1872-6623

10.1016/j.pain.2012.10.018 doi


Amides
Amidohydrolases--antagonists & inhibitors
Analgesics--administration & dosage
Animals
Burns--drug therapy
Carbamates--administration & dosage
Carrageenan--toxicity
Dose-Response Relationship, Drug
Drug Evaluation, Preclinical
Endocannabinoids--physiology
Enzyme Inhibitors--pharmacology
Ethanolamines
Ethers, Cyclic--administration & dosage
HEK293 Cells
Humans
Hyperalgesia--chemically induced
Lysosomes--enzymology
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Oleic Acids--physiology
PPAR alpha--agonists
Pain Perception--drug effects
Palmitic Acids
Radiation Injuries--drug therapy
Rats
Recombinant Fusion Proteins--physiology
Sciatic Nerve--injuries
Tetradecanoylphorbol Acetate--toxicity
Ultraviolet Rays--adverse effects