New tungstenocenes containing 3-hydroxy-4-pyrone ligands: antiproliferative activity on HT-29 and MCF-7 cell lines and binding to human serum albumin studied by fluorescence spectroscopy and molecular modeling methods.

Domínguez-García, Moralba

New tungstenocenes containing 3-hydroxy-4-pyrone ligands: antiproliferative activity on HT-29 and MCF-7 cell lines and binding to human serum albumin studied by fluorescence spectroscopy and molecular modeling methods. [electronic resource] - Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry Feb 2013 - 195-209 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1432-1327

10.1007/s00775-012-0964-2 doi


Antineoplastic Agents--chemistry
Binding Sites
Cell Proliferation--drug effects
Cell Survival--drug effects
Coordination Complexes--chemistry
HT29 Cells
Humans
Hydrogen Bonding
Hydrophobic and Hydrophilic Interactions
Inhibitory Concentration 50
MCF-7 Cells
Models, Molecular
Molecular Docking Simulation
Organometallic Compounds--chemistry
Protein Binding
Serum Albumin
Solubility
Spectrometry, Fluorescence
Tungsten