Sequential activation of classic PKC and estrogen receptor α is involved in estradiol 17ß-D-glucuronide-induced cholestasis.
Barosso, Ismael R
Sequential activation of classic PKC and estrogen receptor α is involved in estradiol 17ß-D-glucuronide-induced cholestasis. [electronic resource] - PloS one 2012 - e50711 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1932-6203
10.1371/journal.pone.0050711 doi
Animals
Carbazoles--pharmacology
Cells, Cultured
Cholestasis--chemically induced
Estradiol--analogs & derivatives
Estrogen Receptor alpha--antagonists & inhibitors
Female
Fulvestrant
Hepatocytes--drug effects
Liver--drug effects
Protein Kinase C--antagonists & inhibitors
Rats
Rats, Wistar
Sequential activation of classic PKC and estrogen receptor α is involved in estradiol 17ß-D-glucuronide-induced cholestasis. [electronic resource] - PloS one 2012 - e50711 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1932-6203
10.1371/journal.pone.0050711 doi
Animals
Carbazoles--pharmacology
Cells, Cultured
Cholestasis--chemically induced
Estradiol--analogs & derivatives
Estrogen Receptor alpha--antagonists & inhibitors
Female
Fulvestrant
Hepatocytes--drug effects
Liver--drug effects
Protein Kinase C--antagonists & inhibitors
Rats
Rats, Wistar