Inverse PPARβ/δ agonists suppress oncogenic signaling to the ANGPTL4 gene and inhibit cancer cell invasion.

Adhikary, T

Inverse PPARβ/δ agonists suppress oncogenic signaling to the ANGPTL4 gene and inhibit cancer cell invasion. [electronic resource] - Oncogene Oct 2013 - 5241-52 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1476-5594

10.1038/onc.2012.549 doi


Acrylonitrile--analogs & derivatives
Angiopoietin-Like Protein 4
Angiopoietins--genetics
Binding Sites
Cell Line, Tumor
Cell Movement
Gene Expression Regulation, Neoplastic
Histone Deacetylases--metabolism
Humans
Neoplasm Invasiveness
PPAR delta--agonists
Piperazines--pharmacology
Retinoid X Receptors--metabolism
Signal Transduction
Sulfonamides--pharmacology
Thiophenes--pharmacology
Transcription Initiation, Genetic--drug effects
Transforming Growth Factor beta--physiology