Pharmacological inhibition of the Wnt acyltransferase PORCN prevents growth of WNT-driven mammary cancer.

Proffitt, Kyle David

Pharmacological inhibition of the Wnt acyltransferase PORCN prevents growth of WNT-driven mammary cancer. [electronic resource] - Cancer research Jan 2013 - 502-7 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1538-7445

10.1158/0008-5472.CAN-12-2258 doi


Acyltransferases
Animals
Benzeneacetamides--pharmacology
Breast Neoplasms--enzymology
Cell Line, Tumor
Humans
Membrane Proteins--antagonists & inhibitors
Mice
Pyridines--pharmacology
Wnt Proteins
Wnt Signaling Pathway
beta Catenin--metabolism