Cerebrospinal fluid matrix metalloproteinases are elevated in cerebral adrenoleukodystrophy and correlate with MRI severity and neurologic dysfunction.

Thibert, Kathryn A

Cerebrospinal fluid matrix metalloproteinases are elevated in cerebral adrenoleukodystrophy and correlate with MRI severity and neurologic dysfunction. [electronic resource] - PloS one 2012 - e50430 p. digital

Publication Type: Journal Article

1932-6203

10.1371/journal.pone.0050430 doi


ATP Binding Cassette Transporter, Subfamily D, Member 1
ATP-Binding Cassette Transporters--genetics
Adrenoleukodystrophy--blood
Blood-Brain Barrier--metabolism
Case-Control Studies
Child
Child, Preschool
Gene Expression
Hematopoietic Stem Cell Transplantation
Humans
Magnetic Resonance Imaging
Male
Matrix Metalloproteinase 10--cerebrospinal fluid
Matrix Metalloproteinase 2--cerebrospinal fluid
Matrix Metalloproteinase 9--cerebrospinal fluid
Mutation
Severity of Illness Index
Tissue Inhibitor of Metalloproteinase-1--cerebrospinal fluid