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Levodopa/benserazide microspheres reduced levodopa-induced dyskinesia by downregulating phosphorylated GluR1 expression in 6-OHDA-lesioned rats.

Yang, Xinxin

Levodopa/benserazide microspheres reduced levodopa-induced dyskinesia by downregulating phosphorylated GluR1 expression in 6-OHDA-lesioned rats. [electronic resource] - Drug design, development and therapy 2012 - 341-7 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

ISSN: 1177-8881

Standard No.: 10.2147/DDDT.S38008 doi

Subjects--Topical Terms:
Animals
Antiparkinson Agents--administration & dosage
Benserazide--administration & dosage
Blotting, Western
Delayed-Action Preparations
Disease Models, Animal
Down-Regulation--drug effects
Drug Carriers--chemistry
Drug Combinations
Dyskinesia, Drug-Induced--etiology
Female
Lactic Acid--chemistry
Levodopa--administration & dosage
Microspheres
Oxidopamine--toxicity
Parkinsonian Disorders--drug therapy
Phosphorylation--drug effects
Polyglycolic Acid--chemistry
Polylactic Acid-Polyglycolic Acid Copolymer
Rats
Rats, Sprague-Dawley
Real-Time Polymerase Chain Reaction
Receptors, AMPA--genetics