Protective mechanisms of simvastatin in experimental periodontal disease.
Dalcico, Roberta
Protective mechanisms of simvastatin in experimental periodontal disease. [electronic resource] - Journal of periodontology Aug 2013 - 1145-57 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
1943-3670
10.1902/jop.2012.120114 doi
Alanine Transaminase--drug effects
Alkaline Phosphatase--drug effects
Alveolar Bone Loss--prevention & control
Animals
Anti-Inflammatory Agents--therapeutic use
Antioxidants--therapeutic use
Aspartate Aminotransferases--drug effects
Bone Morphogenetic Protein 2--drug effects
Female
Gingiva--drug effects
Glutathione--drug effects
Hydroxymethylglutaryl-CoA Reductase Inhibitors--therapeutic use
Interleukin-10--analysis
Interleukin-1beta--drug effects
Malondialdehyde--analysis
Matrix Metalloproteinase 1--drug effects
Matrix Metalloproteinase 8--drug effects
Nitrates--analysis
Nitric Oxide Synthase Type II--drug effects
Nitrites--analysis
Osteoprotegerin--drug effects
Oxidative Stress--drug effects
Periodontitis--prevention & control
Peroxidase--drug effects
RANK Ligand--drug effects
Rats
Rats, Wistar
Receptor Activator of Nuclear Factor-kappa B--drug effects
Simvastatin--therapeutic use
Tumor Necrosis Factor-alpha--drug effects
Protective mechanisms of simvastatin in experimental periodontal disease. [electronic resource] - Journal of periodontology Aug 2013 - 1145-57 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
1943-3670
10.1902/jop.2012.120114 doi
Alanine Transaminase--drug effects
Alkaline Phosphatase--drug effects
Alveolar Bone Loss--prevention & control
Animals
Anti-Inflammatory Agents--therapeutic use
Antioxidants--therapeutic use
Aspartate Aminotransferases--drug effects
Bone Morphogenetic Protein 2--drug effects
Female
Gingiva--drug effects
Glutathione--drug effects
Hydroxymethylglutaryl-CoA Reductase Inhibitors--therapeutic use
Interleukin-10--analysis
Interleukin-1beta--drug effects
Malondialdehyde--analysis
Matrix Metalloproteinase 1--drug effects
Matrix Metalloproteinase 8--drug effects
Nitrates--analysis
Nitric Oxide Synthase Type II--drug effects
Nitrites--analysis
Osteoprotegerin--drug effects
Oxidative Stress--drug effects
Periodontitis--prevention & control
Peroxidase--drug effects
RANK Ligand--drug effects
Rats
Rats, Wistar
Receptor Activator of Nuclear Factor-kappa B--drug effects
Simvastatin--therapeutic use
Tumor Necrosis Factor-alpha--drug effects