Variation in the TLR10/TLR1/TLR6 locus is the major genetic determinant of interindividual difference in TLR1/2-mediated responses.

Mikacenic, C

Variation in the TLR10/TLR1/TLR6 locus is the major genetic determinant of interindividual difference in TLR1/2-mediated responses. [electronic resource] - Genes and immunity Jan 2013 - 52-7 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1476-5470

10.1038/gene.2012.53 doi


Adult
Chromosomes, Human, Pair 4--genetics
Cytokines--blood
Female
Genes, Dominant
Genome-Wide Association Study
Humans
Immunity, Innate--genetics
Lipopeptides--pharmacology
Male
Middle Aged
Phenotype
Polymorphism, Genetic--genetics
Toll-Like Receptor 1--agonists
Toll-Like Receptor 10--genetics
Toll-Like Receptor 2--agonists
Toll-Like Receptor 6--genetics
Toll-Like Receptors--agonists