Lysosomotropic properties of weakly basic anticancer agents promote cancer cell selectivity in vitro.

Ndolo, Rosemary A

Lysosomotropic properties of weakly basic anticancer agents promote cancer cell selectivity in vitro. [electronic resource] - PloS one 2012 - e49366 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1932-6203

10.1371/journal.pone.0049366 doi


Antineoplastic Agents--chemistry
Benzoquinones--chemistry
Biological Transport
Cytosol--metabolism
Drug Design
HL-60 Cells
Humans
Lactams, Macrocyclic--chemistry
Lysosomes--metabolism