CYP2E1-dependent elevation of serum cholesterol, triglycerides, and hepatic bile acids by isoniazid.

Cheng, Jie

CYP2E1-dependent elevation of serum cholesterol, triglycerides, and hepatic bile acids by isoniazid. [electronic resource] - Toxicology and applied pharmacology Jan 2013 - 245-53 p. digital

Publication Type: Journal Article

1096-0333

10.1016/j.taap.2012.10.024 doi


Animals
Antitubercular Agents--toxicity
Bile Acids and Salts--metabolism
Biological Transport--drug effects
Carnitine--metabolism
Chemical and Drug Induced Liver Injury--etiology
Cholesterol--blood
Cytochrome P-450 CYP2E1--metabolism
Fatty Acids, Nonesterified--metabolism
Isoniazid--toxicity
Liver--drug effects
Male
Metabolomics
Mice
Mice, Knockout
Triglycerides--blood