Postexposure application of Fas receptor small-interfering RNA to suppress sulfur mustard-induced apoptosis in human airway epithelial cells: implication for a therapeutic approach.

Keyser, Brian M

Postexposure application of Fas receptor small-interfering RNA to suppress sulfur mustard-induced apoptosis in human airway epithelial cells: implication for a therapeutic approach. [electronic resource] - The Journal of pharmacology and experimental therapeutics Jan 2013 - 308-16 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

1521-0103

10.1124/jpet.112.199935 doi


Animals
Apoptosis--drug effects
Blotting, Western
Bronchoalveolar Lavage Fluid--chemistry
Burns, Inhalation--drug therapy
Caspase 3--metabolism
Cell Line
Cells, Cultured
Chemical Warfare Agents--toxicity
Enzyme Activation--physiology
Enzyme-Linked Immunosorbent Assay
Epithelial Cells--drug effects
Fas Ligand Protein--analysis
Flow Cytometry
Humans
Male
Mustard Gas--toxicity
RNA, Small Interfering--pharmacology
Rats
Rats, Sprague-Dawley
Respiratory System--cytology
Transfection
fas Receptor--antagonists & inhibitors