Improved supersaturation and oral absorption of dutasteride by amorphous solid dispersions.

Beak, In-Hwan

Improved supersaturation and oral absorption of dutasteride by amorphous solid dispersions. [electronic resource] - Chemical & pharmaceutical bulletin 2012 - 1468-73 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1347-5223

10.1248/cpb.c12-00563 doi


2-Hydroxypropyl-beta-cyclodextrin
5-alpha Reductase Inhibitors--administration & dosage
Administration, Oral
Animals
Azasteroids--administration & dosage
Cellulose--analogs & derivatives
Dutasteride
Excipients--chemistry
Hypromellose Derivatives
Male
Methylcellulose--analogs & derivatives
Methylmethacrylates--chemistry
Povidone--chemistry
Rats
Rats, Sprague-Dawley
Solubility
beta-Cyclodextrins--chemistry