Deletion of the viral anti-apoptotic gene F1L in the HIV/AIDS vaccine candidate MVA-C enhances immune responses against HIV-1 antigens.

Perdiguero, Beatriz

Deletion of the viral anti-apoptotic gene F1L in the HIV/AIDS vaccine candidate MVA-C enhances immune responses against HIV-1 antigens. [electronic resource] - PloS one 2012 - e48524 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0048524 doi


AIDS Vaccines--immunology
Amino Acid Sequence
Animals
Apoptosis--genetics
Base Sequence
CD8-Positive T-Lymphocytes--immunology
Cell Line
Chick Embryo
Cytokines--metabolism
Dendritic Cells--immunology
Epitopes, T-Lymphocyte--immunology
Gene Deletion
Gene Expression
Gene Order
Genetic Vectors--genetics
HIV Antigens--genetics
HIV Envelope Protein gp120--chemistry
HIV-1--genetics
Human Immunodeficiency Virus Proteins--chemistry
Humans
Immunologic Memory--immunology
Interferon Type I--metabolism
Macrophages--immunology
Mice
Molecular Sequence Data
T-Lymphocytes--immunology
Vaccinia virus--genetics
Viral Proteins--genetics