Attenuation of corneal myofibroblast development through nanoparticle-mediated soluble transforming growth factor-β type II receptor (sTGFβRII) gene transfer.

Sharma, Ajay

Attenuation of corneal myofibroblast development through nanoparticle-mediated soluble transforming growth factor-β type II receptor (sTGFβRII) gene transfer. [electronic resource] - Molecular vision 2012 - 2598-607 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

1090-0535


Actins--biosynthesis
Apoptosis--drug effects
Cell Survival--drug effects
Cells, Cultured
Cornea--drug effects
Fibrosis--chemically induced
Humans
Immunoglobulin Fc Fragments--chemistry
Lipids--chemistry
Myofibroblasts--drug effects
Nanoparticles--chemistry
Plasmids--chemistry
Polyethyleneimine--chemistry
Protein Serine-Threonine Kinases--chemistry
Receptor, Transforming Growth Factor-beta Type II
Receptors, Transforming Growth Factor beta--chemistry
Solubility
Transfection--methods
Transforming Growth Factor beta1--adverse effects