Conditional deletion of cytokine receptor chains reveals that IL-7 and IL-15 specify CD8 cytotoxic lineage fate in the thymus.

McCaughtry, Tom M

Conditional deletion of cytokine receptor chains reveals that IL-7 and IL-15 specify CD8 cytotoxic lineage fate in the thymus. [electronic resource] - The Journal of experimental medicine Nov 2012 - 2263-76 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Intramural

1540-9538

10.1084/jem.20121505 doi


Animals
CD8-Positive T-Lymphocytes--immunology
Cell Differentiation--immunology
Cell Lineage--immunology
Flow Cytometry
Interleukin Receptor Common gamma Subunit--genetics
Interleukin-7--metabolism
Mice
Mice, Inbred C57BL
Mice, Knockout
Receptors, Cytokine--genetics
Receptors, Interleukin-15--genetics
Receptors, Interleukin-7--genetics
Thymus Gland--cytology