Impact of epidermal growth factor receptor (EGFR) cell surface expression levels on effector mechanisms of EGFR antibodies.
Derer, Stefanie
Impact of epidermal growth factor receptor (EGFR) cell surface expression levels on effector mechanisms of EGFR antibodies. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Dec 2012 - 5230-9 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1550-6606
10.4049/jimmunol.1202037 doi
Animals
Antibodies, Monoclonal--pharmacology
Antibodies, Monoclonal, Humanized
Antineoplastic Agents--pharmacology
Carcinoma, Non-Small-Cell Lung--drug therapy
Cell Line, Tumor
Cetuximab
Complement System Proteins--pharmacology
Cricetinae
ErbB Receptors--genetics
Gene Expression--immunology
Gene Knockdown Techniques
Humans
Immunoglobulin Fab Fragments--pharmacology
Immunoglobulin Fc Fragments--pharmacology
Killer Cells, Natural--cytology
Lung Neoplasms--drug therapy
Monocytes--cytology
RNA, Small Interfering--genetics
Transfection
Tumor Cells, Cultured
Impact of epidermal growth factor receptor (EGFR) cell surface expression levels on effector mechanisms of EGFR antibodies. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Dec 2012 - 5230-9 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1550-6606
10.4049/jimmunol.1202037 doi
Animals
Antibodies, Monoclonal--pharmacology
Antibodies, Monoclonal, Humanized
Antineoplastic Agents--pharmacology
Carcinoma, Non-Small-Cell Lung--drug therapy
Cell Line, Tumor
Cetuximab
Complement System Proteins--pharmacology
Cricetinae
ErbB Receptors--genetics
Gene Expression--immunology
Gene Knockdown Techniques
Humans
Immunoglobulin Fab Fragments--pharmacology
Immunoglobulin Fc Fragments--pharmacology
Killer Cells, Natural--cytology
Lung Neoplasms--drug therapy
Monocytes--cytology
RNA, Small Interfering--genetics
Transfection
Tumor Cells, Cultured