Vascular niche E-selectin regulates hematopoietic stem cell dormancy, self renewal and chemoresistance.

Winkler, Ingrid G

Vascular niche E-selectin regulates hematopoietic stem cell dormancy, self renewal and chemoresistance. [electronic resource] - Nature medicine Nov 2012 - 1651-7 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1546-170X

10.1038/nm.2969 doi


Animals
Bone Marrow Cells--cytology
Cell Differentiation
Cell Lineage--drug effects
Cell Proliferation--drug effects
Cell Survival--drug effects
E-Selectin--genetics
Endothelial Cells--cytology
Gene Expression Regulation--drug effects
Hematopoietic Stem Cell Transplantation
Hematopoietic Stem Cells--metabolism
Hydroxyurea--pharmacology
Ligands
Mice
Mice, Inbred C57BL
Mice, Knockout
Neutrophils--cytology
Radiation