Design, Prins-cyclization reaction promoting diastereoselective synthesis of 10 new tetrahydropyran derivatives and in vivo antinociceptive evaluations.

Capim, Saulo L

Design, Prins-cyclization reaction promoting diastereoselective synthesis of 10 new tetrahydropyran derivatives and in vivo antinociceptive evaluations. [electronic resource] - European journal of medicinal chemistry Dec 2012 - 1-11 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1768-3254

10.1016/j.ejmech.2012.09.046 doi


Abdominal Pain--chemically induced
Acetic Acid--metabolism
Analgesics--chemical synthesis
Animals
Cyclization
Dose-Response Relationship, Drug
Drug Design
Male
Mice
Molecular Structure
Primed In Situ Labeling
Pyrans--chemical synthesis
Stereoisomerism