Regression of human prostate cancer xenografts in mice by AMG 212/BAY2010112, a novel PSMA/CD3-Bispecific BiTE antibody cross-reactive with non-human primate antigens.

Friedrich, Matthias

Regression of human prostate cancer xenografts in mice by AMG 212/BAY2010112, a novel PSMA/CD3-Bispecific BiTE antibody cross-reactive with non-human primate antigens. [electronic resource] - Molecular cancer therapeutics Dec 2012 - 2664-73 p. digital

Publication Type: Journal Article

1538-8514

10.1158/1535-7163.MCT-12-0042 doi


Animals
Antibodies, Bispecific--genetics
Antigens, Surface--immunology
CD3 Complex--genetics
CHO Cells
Cricetinae
Cross Reactions
Female
Glutamate Carboxypeptidase II--immunology
Haplorhini
Humans
Immunization, Passive--methods
Macaca fascicularis
Male
Mice
Mice, Inbred BALB C
Mice, Inbred NOD
Mice, SCID
Prostatic Neoplasms--immunology
Transfection
Xenograft Model Antitumor Assays