Idebenone protects against retinal damage and loss of vision in a mouse model of Leber's hereditary optic neuropathy.

Heitz, Fabrice D

Idebenone protects against retinal damage and loss of vision in a mouse model of Leber's hereditary optic neuropathy. [electronic resource] - PloS one 2012 - e45182 p. digital

Publication Type: Journal Article

1932-6203

10.1371/journal.pone.0045182 doi


Administration, Oral
Animals
Antioxidants--pharmacology
Cell Line
Cell Survival--drug effects
Disease Models, Animal
Drug Administration Schedule
Electron Transport Complex I--genetics
Humans
Intravitreal Injections
Male
Mice
Mitochondria--drug effects
Mutation
Optic Atrophy, Hereditary, Leber--chemically induced
Retinal Ganglion Cells--drug effects
Rotenone
Ubiquinone--analogs & derivatives
Visual Acuity--drug effects