Opiate addiction and cocaine addiction: underlying molecular neurobiology and genetics.

Kreek, Mary Jeanne

Opiate addiction and cocaine addiction: underlying molecular neurobiology and genetics. [electronic resource] - The Journal of clinical investigation Oct 2012 - 3387-93 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Review

1558-8238

10.1172/JCI60390 doi


Animals
Basal Ganglia--drug effects
Cocaine-Related Disorders--drug therapy
Dopamine--physiology
Dopaminergic Neurons--physiology
Gene Expression Regulation--drug effects
Genetic Predisposition to Disease
Humans
Hypothalamo-Hypophyseal System--physiopathology
Limbic System--drug effects
Methadone--therapeutic use
Mice
Mice, Knockout
Neuropeptides--physiology
Opioid-Related Disorders--drug therapy
Pharmacogenetics
Pituitary-Adrenal System--physiopathology
Rats
Receptors, Dopamine--drug effects
Receptors, Opioid--drug effects
Receptors, Opioid, mu--drug effects
Reward
Stress, Physiological
Stress, Psychological--physiopathology