Downregulation of protein kinase CK2 induces autophagic cell death through modulation of the mTOR and MAPK signaling pathways in human glioblastoma cells.

Olsen, Birgitte B

Downregulation of protein kinase CK2 induces autophagic cell death through modulation of the mTOR and MAPK signaling pathways in human glioblastoma cells. [electronic resource] - International journal of oncology Dec 2012 - 1967-76 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1791-2423

10.3892/ijo.2012.1635 doi


Autophagy--genetics
Casein Kinase II--genetics
Cell Line, Tumor
Down-Regulation--genetics
Glioblastoma--genetics
Humans
Mitogen-Activated Protein Kinase 1--metabolism
Mitogen-Activated Protein Kinase 3--metabolism
Mitogen-Activated Protein Kinases--metabolism
RNA Interference
Reactive Oxygen Species--metabolism
Signal Transduction
TOR Serine-Threonine Kinases--metabolism