Tyrosine phosphorylation of the p21 cyclin-dependent kinase inhibitor facilitates the development of proneural glioma.

Hukkelhoven, Ellen

Tyrosine phosphorylation of the p21 cyclin-dependent kinase inhibitor facilitates the development of proneural glioma. [electronic resource] - The Journal of biological chemistry Nov 2012 - 38523-30 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1083-351X

10.1074/jbc.M112.366542 doi


Amino Acid Sequence
Animals
Cell Proliferation
Central Nervous System Neoplasms--metabolism
Cyclin D1--metabolism
Cyclin-Dependent Kinase 4--metabolism
Cyclin-Dependent Kinase Inhibitor p21--metabolism
Cyclin-Dependent Kinase Inhibitor p27--metabolism
Disease Models, Animal
Gene Expression Regulation, Neoplastic
Glioblastoma--metabolism
Glioma--pathology
HEK293 Cells
Humans
Mice
Molecular Sequence Data
Mutation
Phosphorylation
Tyrosine--chemistry