Substitutions at residue 211 in the prion protein drive a switch between CJD and GSS syndrome, a new mechanism governing inherited neurodegenerative disorders.
Peoc'h, Katell
Substitutions at residue 211 in the prion protein drive a switch between CJD and GSS syndrome, a new mechanism governing inherited neurodegenerative disorders. [electronic resource] - Human molecular genetics Dec 2012 - 5417-28 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1460-2083
10.1093/hmg/dds377 doi
Amino Acid Substitution
Cloning, Molecular
Creutzfeldt-Jakob Syndrome--genetics
Gerstmann-Straussler-Scheinker Disease--genetics
Humans
Models, Molecular
Molecular Dynamics Simulation
Mutation
Phenotype
Phosphorylation
Plaque, Amyloid--genetics
Prions--genetics
Protein Conformation
Substitutions at residue 211 in the prion protein drive a switch between CJD and GSS syndrome, a new mechanism governing inherited neurodegenerative disorders. [electronic resource] - Human molecular genetics Dec 2012 - 5417-28 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1460-2083
10.1093/hmg/dds377 doi
Amino Acid Substitution
Cloning, Molecular
Creutzfeldt-Jakob Syndrome--genetics
Gerstmann-Straussler-Scheinker Disease--genetics
Humans
Models, Molecular
Molecular Dynamics Simulation
Mutation
Phenotype
Phosphorylation
Plaque, Amyloid--genetics
Prions--genetics
Protein Conformation