The apolipoprotein-E-mimetic COG112 protects amyloid precursor protein intracellular domain-overexpressing animals from Alzheimer's disease-like pathological features.

Ghosal, Kaushik

The apolipoprotein-E-mimetic COG112 protects amyloid precursor protein intracellular domain-overexpressing animals from Alzheimer's disease-like pathological features. [electronic resource] - Neuro-degenerative diseases 2013 - 51-8 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1660-2862

10.1159/000341299 doi


Alzheimer Disease--drug therapy
Amyloid beta-Protein Precursor--genetics
Animals
Apolipoproteins E--metabolism
Female
Gliosis--drug therapy
Hippocampus--metabolism
Inflammation--drug therapy
Male
Mice
Mice, Inbred C57BL
Mice, Transgenic
Neurogenesis--drug effects
Peptides--pharmacology
Phosphorylation--drug effects
tau Proteins--metabolism